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Editorial Board
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CO2
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Editorial
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1-2
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Detection of the synthetic drug 4-fluoroamphetamine (4-FA) in serum and urine
05 May 2011
Abstract: 4-Fluoroamphetamine (4-FA) was detected in the blood and urine of two individuals suspected for driving under the influence (DUI). The test for amphetamines in urine subjected to immunoassay...
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J. Röhrich,
J. Becker,
T. Kaufmann,
S. Zörntlein,
R. Urban
et al.
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3-7
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Identification of 1-butyl-3-(1-(4-methyl)naphthoyl)indole in a herbal mixture
05 May 2011
Abstract: Besides the cannabinoid mimetic JWH-073, a novel 4 methylnaphthoyl homologue of JWH-073 was detected in a herbal mixture. The structure of the compound was elucidated after thin layer chroma...
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F. Westphal,
F.D. Sönnichsen,
S. Thiemt
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8-13
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The prevalence of drugs in injured drivers
07 March 2011
Abstract: In mid 2009 Victoria introduced compulsory drug testing of blood taken from all injured drivers taken to hospital. Δ9-Tetrahydrocannabinol (THC), methylamphetamine (MA) and 3,4-methylenediox...
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Olaf H. Drummer,
Irene Kourtis,
Jochen Beyer,
Penny Tayler,
Martin Boorman,
Dimitri Gerostamoulos
et al.
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14-17
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Concentrations of free-morphine in peripheral blood after recent use of heroin in overdose deaths and in apprehended drivers
25 February 2011
Abstract: The concentration of free-morphine was determined in peripheral (femoral) blood from heroin-related deaths and compared with the concentration in venous blood from impaired drivers. The pres...
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A.W. Jones,
A. Holmgren,
J. Ahlner
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18-24
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Amphetamine, cocaine and cannabinoids use among truck drivers on the roads in the State of Sao Paulo, Brazil
21 April 2011
Abstract: Drugs are important risk factors for traffic accidents. In Brazil, truck drivers report using amphetamines to maintain their extensive work schedule and stay awake. These drugs can be obtain...
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V. Leyton,
D.M. Sinagawa,
K.C.B.G. Oliveira,
W. Schmitz,
G. Andreuccetti,
B.S. De Martinis,
M. Yonamine,
D.R. Munoz
et al.
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25-27
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The incidence of drugs of impairment in oral fluid from random roadside testing
13 June 2011
Abstract: Oral fluid (OF) has become a popular specimen to test for presence of drugs, particularly in regards to road safety. In Victoria, OF specimens from drivers have been used to test for the pre...
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Mark Chu,
Dimitri Gerostamoulos,
Jochen Beyer,
Luke Rodda,
Martin Boorman,
Olaf H. Drummer
et al.
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28-31
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Significantly increased detection rate of drugs of abuse in urine following the introduction of new German driving licence re-granting guidelines
18 November 2011
Abstract: In this paper we present the first assessment of the new German driving licence re-granting medical and psychological assessment (MPA) guidelines by comparing over 3500 urine samples tested ...
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Ronald Agius,
Thomas Nadulski,
Hans-Gerhard Kahl,
Bertin Dufaux
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32-37
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Validation of LUCIO®-Direct-ELISA kits for the detection of drugs of abuse in urine: Application to the new German driving licence re-granting guidelines
10 November 2011
Abstract: LUCIO®-Direct-enzyme linked immunosorbent assay (ELISA) tests were validated for the screening of drugs of abuse cannabis, opiates, amphetamines and cocaine in urine for the new German medic...
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Ronald Agius,
Thomas Nadulski,
Christine Moore
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38-45
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Prevalence of drug abuse among workers: Strengths and pitfalls of the recent Italian Workplace Drug Testing (WDT) legislation
11 April 2011
Abstract: Background: In 2008 a Workplace Drug Testing (WDT) law became effective in Italy for workers involved in public/private transportation, oil/gas companies, and explosives/fireworks industry w...
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Isabel Kazanga,
Silvia Tameni,
Alberto Piccinotti,
Ivan Floris,
Gabriele Zanchetti,
Aldo Polettini
et al.
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46-50
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Ethyl glucuronide in human hair after daily consumption of 16 or 32 g of ethanol for 3 months
02 March 2011
Abstract: The overall objectives of the study were to develop a sensitive method for ethyl glucuronide (EtG) determination in hair and then investigate if a low or moderate intake of ethanol could be ...
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Robert Kronstrand,
Linda Brinkhagen,
Fredrik H. Nyström
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51-55
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Analysis of drugs of abuse in hair: Evaluation of the immunochemical method VMA-T vs. LC–MS/MS or GC–MS
24 October 2011
Abstract: Hair analysis is an elaborate and time-consuming multi-step process. The immunometric test VMA-T from Comedical has been evaluated as screening assay for hair analysis. From routine work, au...
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Markus R. Baumgartner,
Rosetta Guglielmello,
Monique Fanger,
Thomas Kraemer
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56-59
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Evaluation of two immunoassay procedures for drug testing in hair samples
25 May 2011
Abstract: A preliminary initial enzyme-linked immunosorbent assay (LUCIO®-Direct ELISA kit) and a preliminary DRI® enzyme immunoassay were evaluated for drug detection in head hair with respect to low...
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F. Musshoff,
K.M. Kirschbaum,
K. Graumann,
C. Herzfeld,
H. Sachs,
B. Madea
et al.
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60-63
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Detection and validated quantification of 21 benzodiazepines and 3 “z-drugs” in human hair by LC–MS/MS
29 August 2011
Abstract: A method for detection and quantification of 21 benzodiazepines and the pharmacologically related “z-drugs” in human hair samples was developed and fully validated using liquid chromatograph...
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Kristina Y. Rust,
Markus R. Baumgartner,
Natascha Meggiolaro,
Thomas Kraemer
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64-72
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Segmental hair analysis can demonstrate external contamination in postmortem cases
28 February 2011
Abstract: Excluding laboratory mistakes, a false positive hair result can be observed in case of contamination from environmental pollution (external contamination) or after drug incorporation into th...
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Pascal Kintz
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73-76
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Hair testing and self-report of cocaine use
06 June 2011
Abstract: Hair analysis is a useful tool in both clinical and forensic fields: it allows information about drugs of abuse (DOA) consumption to be obtained. However, in spite of analytical results, som...
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Claudia Vignali,
Cristiana Stramesi,
Micol Vecchio,
Angelo Groppi
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77-80
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Simultaneous analysis of psychotropic phenylalkylamines in oral fluid by GC–MS with automated SPE and its application to legal cases
07 March 2011
Abstract: Phenylalkylamine derivatives, such as methamphetamine (MA), amphetamine (AM), 3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyamphetamine (MDA), phentermine (PT), fenfluramine (F...
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Hyeyoung Choi,
Seungkyung Baeck,
Moonhee Jang,
Sooyeun Lee,
Hwakyung Choi,
Heesun Chung
et al.
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81-87
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Oral fluid results compared to self reports of recent cocaine and heroin use by methadone maintenance patients
07 March 2011
Abstract: Introduction: Although self reports of illicit drug use may not be reliable, this information is frequently collected and relied upon by national drug surveys and by counselors in drug treat...
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Edward J. Cone
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88-91
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A rapid and sensitive method for the identification of delta-9-tetrahydrocannabinol in oral fluid by liquid chromatography–tandem mass spectrometry
02 March 2011
Abstract: A fast and sensitive method was developed for detecting delta-9-tetrahydrocannabinol (THC) in oral fluid by liquid chromatography–tandem mass spectrometry (LC–MS/MS). The method is suitable ...
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Anna Molnar,
John Lewis,
Philip Doble,
Glyn Hansen,
Tatiana Prolov,
Shanlin Fu
et al.
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92-96
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Sexual abuse and anti-wrinkle cream: Evidence from octocrylene
03 March 2011
Abstract: We report an alleged case of sexual assault in which an anti-wrinkle cream could have been used as a lubricant. Three anorectal samples taken from the victim were given to us in an attempt t...
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Carole Jamey,
Antoine Tracqui,
Bertrand Ludes
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97-100
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Fatal tolperisone poisoning: Autopsy and toxicology findings in three suicide cases
20 June 2011
Abstract: Tolperisone (Mydocalm®) is a centrally acting muscle relaxant with few sedative side effects that is used for the treatment of chronic pain conditions. We describe three cases of suicidal to...
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Frank Sporkert,
Christophe Brunel,
Marc P. Augsburger,
Patrice Mangin
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101-104
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Determination of venlafaxine in post-mortem whole blood by HS-SPME and GC-NPD
06 June 2011
Abstract: Venlafaxine is a phenethylamine derivative widely prescribed for the treatment of depression which inhibits both serotonin and norepinephrine reuptake (SNRI). In treatment with antidepressan...
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O. Mastrogianni,
G. Theodoridis,
K. Spagou,
D. Violante,
T. Henriques,
A. Pouliopoulos,
K. Psaroulis,
H. Tsoukali,
N. Raikos
et al.
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105-109
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A fatal intoxication by chloroprene
21 April 2011
Abstract: Objective Chloroprene, 2-chloro-1,3 butadiene, is a volatile synthetic liquid. The chloroprene monomer is extremely reactive and is used for the production of latexes and synthetic rubber su...
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Annette Rickert,
Benno Hartung,
Bernd Kardel,
Johanna Teloh,
Thomas Daldrup
et al.
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110-113
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Reporting a sudden death due to accidental gasoline inhalation
28 February 2011
Abstract: The investigation of uncertain fatalities requires accurate determination of the cause of death, with assessment of all factors that may have contributed to it. Gasoline is a complex and hig...
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María Antonia Martínez,
Salomé Ballesteros,
Rafael Alcaraz
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114-120
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Evidence of Haldol (haloperidol) long-term intoxication
03 March 2011
Abstract: A case of intoxication by haloperidol is reported. Haloperidol is a butyrophenone derivative commonly used in many hospital units as an antipsychotic agent. Adverse reactions due to haloperi...
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Enrico Gerace,
Alberto Salomone,
Sergio Pellegrino,
Marco Vincenti
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121-123
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Characterization of pentoxyverine metabolites in urine using GC/MS after intoxication with Silomat® cough drops
31 March 2011
Abstract: A nearly two and a half year old boy was hospitalized after showing symptoms of disorientation and hallucination. The parents remembered the child playing with a bottle of Silomat® cough dro...
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F. Westphal,
Th. Junge,
L. Radünz,
J. Stegk,
G. Rochholz
et al.
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124-135
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Development and validation of a sensitive UPLC–MS/MS method for the analysis of narcotic analgesics in urine and whole blood in forensic context
28 February 2011
Abstract: Narcotic analgesics are widely (ab) used and sometimes only occur in low concentrations in biological samples. Therefore, a highly sensitive liquid chromatography tandem mass spectrometry me...
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Ruth Verplaetse,
Jan Tytgat
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136-145
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Method validation of a survey of thevetia cardiac glycosides in serum samples
07 March 2011
Abstract: A sensitive and specific liquid chromatography tandem mass spectrometry (HPLC–ESI+-MS/MS) procedure was developed and validated for the identification and quantification of thevetin B and fu...
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Sarah Kohls,
Barbara Scholz-Böttcher,
Jürgen Rullkötter,
Jörg Teske
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146-151
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Assessment of the stability of 30 antipsychotic drugs in stored blood specimens
28 March 2011
Abstract: The stability of 30 common antipsychotics (APs) in spiked whole blood was investigated over ten weeks in a preliminary experiment (designated “P experiment”). Pools of blank blood spiked wit...
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Eva Saar,
Dimitri Gerostamoulos,
Olaf H. Drummer,
Jochen Beyer
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152-158
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Stability of diazepam in blood samples at different storage conditions and in the presence of alcohol
06 May 2011
Abstract: Diazepam is one of the mostly used benzodiazepines and it is frequently analyzed in different biological samples, especially blood samples. The diazepam stability in the sample matrices is a...
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V.N. Atanasov,
S. Stoykova,
A. Runiov,
T. Dimitrova,
D. Aleksandrova,
S. Tsakovski,
M. Mitewa
et al.
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159-163
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Characteristics of cannabinoids composition of Cannabis plants grown in Northern Thailand and its forensic application
03 June 2011
Abstract: The Thai government has recognized the possibility for legitimate cultivation of hemp. Further study of certain cannabinoid characteristics is necessary in establishing criteria for regulati...
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Prapatsorn Tipparat,
Surapol Natakankitkul,
Pipop Chamnivikaipong,
Sirot Chutiwat
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164-170
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THCVA-A – A new additional marker for illegal cannabis consumption
01 April 2011
Abstract: The aim of the present investigations was to find markers for differentiating between the consumption of illegal cannabis products and legal medication containing fully synthetic Δ9-tetrahyd...
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Lars Radünz,
Folker Westphal,
Edmund Maser,
Gertrud Rochholz
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171-174
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Cross-examination of liquid–liquid extraction (LLE) and solid-phase microextraction (SPME) methods for impurity profiling of methamphetamine
07 March 2011
Abstract: Impurities in 48 methamphetamine (MA) samples were analyzed by liquid–liquid extraction (LLE) and headspace solid-phase microextraction (HS-SPME) methods. MPS-2 autosampler was used to impro...
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Jaesin Lee,
Yonghoon Park,
Wonkyung Yang,
Heesun Chung,
Wonjun Choi,
Hiroyuki Inoue,
Kenji Kuwayama,
Jeonghill Park
et al.
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175-178
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Effects of synthetic cannabinoids on electroencephalogram power spectra in rats
03 June 2011
Abstract: Several synthetic cannabinoids have recently been distributed as psychoactive adulterants in many herbal products on the illegal drug market around the world. However, there is little inform...
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Nahoko Uchiyama,
Ruri Kikura-Hanajiri,
Naomi Matsumoto,
Zhi-Li Huang,
Yukihiro Goda,
Yoshihiro Urade
et al.
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179-183
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Serotonin toxicity involving MDMA (ecstasy) and moclobemide
16 May 2011
Abstract: The use of MDMA (ecstasy) in Australia is a widespread and growing problem, promoting acute toxicity and disease which can lead to premature death in users. We report four cases of fatal ser...
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J.L. Pilgrim,
D. Gerostamoulos,
N. Woodford,
Olaf H. Drummer
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184-188
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Microbial ethanol production: Experimental study and multivariate evaluation
07 April 2011
Abstract: Ethanol can be produced from all the postmortem available substrates, though with higher rates and yields from carbohydrates, during the early stages of putrefaction. The so-called higher al...
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Vassiliki A. Boumba,
Vangelis Economou,
Nikolaos Kourkoumelis,
Panagiota Gousia,
Chrissanthy Papadopoulou,
Theodore Vougiouklakis
et al.
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189-198
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