Forensic Science International
Volume 196, Issue 1 , Pages 27-31, 20 March 2010

Prenatal hair development: Implications for drug exposure determination

Division of Clinical Pharmacology & Toxicology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada

Received 12 June 2009; accepted 21 July 2009. published online 14 January 2010.

Abstract 

Neonatal hair is a clinically important toxicological matrix, as it allows determination of in utero drug exposure. This paper serves to review the physiological development of the hair follicle and hair production during fetal life. An understanding of the mechanisms and timing of hair development in the prenatal period is critical to effectively assessing the time window of exposure determination associated with toxicological analysis of neonatal hair.

Keywords: Hair, Fetal, Neonatal, Toxicology, Drugs

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PII: S0379-0738(09)00525-8

doi:10.1016/j.forsciint.2009.12.024

Forensic Science International
Volume 196, Issue 1 , Pages 27-31, 20 March 2010

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