Forensic Science International
Volume 116, Issue 1 , Pages 55-58, 1 February 2001

Sequence analysis and population data on the ‘new’ short tandem repeat locus D5S2360☆

  • Lotte Henke

      Affiliations

    • Institut für Blutgruppenforschung, Hohenzollernring 57, 50672 Koeln, Germany
    • ,
  • Rolf Fimmers

      Affiliations

    • Institut für Medizinische Biometrie, Informatik und Epidemiologie der Rheinischen Friedrich-Wilhelms-Universität, Bonn, Germany
    • ,
  • Jürgen Reinhold

      Affiliations

    • Labor Dr. Arnold, Wuerzburg, Germany
    • ,
  • Marlies Dülmer

      Affiliations

    • Institut für Blutgruppenforschung, Hohenzollernring 57, 50672 Koeln, Germany
    • ,
  • Sabine Cleef

      Affiliations

    • Institut für Blutgruppenforschung, Hohenzollernring 57, 50672 Koeln, Germany
    • ,
  • Johann Arnold

      Affiliations

    • Labor Dr. Arnold, Wuerzburg, Germany
    • ,
  • Jürgen Henke

      Affiliations

    • Institut für Blutgruppenforschung, Hohenzollernring 57, 50672 Koeln, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-221-253037; fax: +49-221-251247

Received 24 January 2000; received in revised form 18 July 2000; accepted 20 July 2000.

Abstract 

We have studied the sequence structure and population genetics of a ‘new’ short tandem repeat polymorphism at locus D5S2360 in German Caucasians. Sequencing at this locus revealed a considerable variation, which is characterized by a tetranucleotide (AGAT)n repeat pattern with (GAT), (AGATT), and (AG) repeats dispersed throughout the alleles. These microvariations do not necessarily alter the size of the alleles. They may vary by one or two pairs or they may remain unchanged in size. At locus D5S2360 we observed 33 allelic lengths comprising at least 36 different alleles. Population data revealed a high polymorphism with a heterozygosity rate of approximately 92.5%.

Keywords:  DNA, STR, D5S2360, Sequence analysis, Population genetics, Forensic genetics

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☆ Preliminary results were presented at the 18th ISFH congress, San Francisco, CA, USA, 17–21 August 1999.

PII: S0379-0738(00)00349-2

Forensic Science International
Volume 116, Issue 1 , Pages 55-58, 1 February 2001

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