Forensic Science International
Volume 116, Issue 1 , Pages 9-14 , 1 February 2001

Blood concentrations of tetracaine and its metabolite following spinal anesthesia

  • Keiko Kudo

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Yukiko Hino

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Noriaki Ikeda

      Affiliations

    • Department of Forensic Pathology and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-92-642-6124; fax: +81-92-642-6126
    • ,
  • Hidefumi Inoue

      Affiliations

    • Department of Anesthesiology & Critical Care Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
    • ,
  • Shosuke Takahashi

      Affiliations

    • Department of Anesthesiology & Critical Care Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan

Received 19 May 2000 ,Revised 22 June 2000 ,Accepted 27 June 2000.

References 

  1. Altman RS, Smith-Coggins R, Ampel LL. Local anesthetics. Ann. Emerg. Med. 1985;14:1209–1217
  2. Fukui M. Medicolegal study of spinal anesthesia. Jpn. J. Legal Med. 1970;24:136–158
  3. Hino Y, Ikeda N, Kudo K, Tsuji A. Sensitive and selective determination of tetracaine and its metabolite in human samples by gas chromatography–mass spectrometry. J. Anal. Toxicol. 2000;24:165–169
  4. Van Kan HJM, Egberts ACG, Rijnvos WPM, Ter Pelkwijk NJ, Lenderink AW. Tetracaine versus lidocaine-prilocaine for preventing venipuncture-induced pain in children. Am. J. Health-Syst. Pharm. 1997;54:388–392
  5. Terndrup TE, Walls HC, Mariani PJ, Gavula DP, Madden CM, Cantor RM. Plasma cocaine and tetracaine levels following application of topical anesthesia in children. Ann. Emerg. Med. 1992;21:162–166
  6. Mazumdar B, Tomlinson AA, Faulder GC. Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine. Br. J. Anaesth. 1991;67:432–436
  7. Kambam JR, Horton B, Parris WCV, Hyman SA, Berman ML, Sastry BVR. Pseudocholinesterase activity in human cerebrospinal fluid. Anesth. Analg. 1989;68:486–488
  8. Takasaki M, Oh-oka T, Doi K, Kosaka Y. Blood levels of mepivacaine during continuous epidural anesthesia. Anesth. Analg. 1987;66:337–340

PII: S0379-0738(00)00342-X

Forensic Science International
Volume 116, Issue 1 , Pages 9-14 , 1 February 2001

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