Forensic Science International
Volume 115, Issue 3 , Pages 207-217 , 15 January 2001

Sequenced allelic ladders and population genetics of a new STR multiplex system

  • Stephanie Watson

      Affiliations

    • The Forensic Science Service, Priory House, Gooch Street North, Birmingham B5 6QQ, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44-121-617-6917; fax: +44-121-666-6125
    • ,
  • Rachel Allsop

      Affiliations

    • The Forensic Science Service, Priory House, Gooch Street North, Birmingham B5 6QQ, UK
    • ,
  • Lindsey Foreman

      Affiliations

    • The Forensic Science Service, 109 Lambeth Road London, London SE1 7LP, UK
    • ,
  • Zoe Kelsey

      Affiliations

    • The Forensic Science Service, Priory House, Gooch Street North, Birmingham B5 6QQ, UK
    • ,
  • Peter Gill

      Affiliations

    • The Forensic Science Service, Priory House, Gooch Street North, Birmingham B5 6QQ, UK

Received 12 December 1999 ,Revised 11 June 2000 ,Accepted 14 June 2000.

References 

  1. Kimpton CP, Gill P, Walton A, Urquhart A, Millican ES, Adams M. Automated DNA profiling employing multiplex amplification of short tandem repeat loci. PCR Methods Appl. 1993;3:13–22
  2. Sparkes R, Kimpton C, Watson S, Oldroyd NJ, Clayton T, Barnett L, et al. The validation of a 7-locus multiplex STR test for use in forensic casework I. Int. J. Legal Med. 1996;109:186–194
  3. Sparkes R, Kimpton C, Gillbard S, Carne P, Anderson J, Oldroyd NJ, et al. The validation of a 7-locus multiplex STR test for use in forensic casework II. Int. J. Legal Med. 1996;109:195–204
  4. Hagelberg E, Gray IC, Jeffreys AJ. Identification of the skeletal remains of a murder victim by DNA analysis. Nature. 1991;352:427–429
  5. Jeffreys AJ, Allen MJ, Hagelberg E, Sonnberg A. Identification of the remains of Josef Mengele by DNA analysis. Forensic Sci. Int. 1992;56:65–76
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  7. Gill P, Ivanov P, Kimpton CP, Piercy R, Benson NJ, Tully G, et al. Identification of the Romanov family by DNA analysis. Genetics. 1993;6:130–153
  8. Ziegle JS, Su Y, Cotcoran KP, Nie L, Maryrand PE, Hoff LB, et al. Application of automated DNA sizing technology for genotyping microsatellite loci. Genomics. 1992;14:1026–1031
  9. Fregeau CJ, Fourney RM. DNA typing with fluorescently tagged short tandem repeats: a sensitive and accurate approach to human identification. Biotechniques. 1993;15:100–109
  10. Robertson JM, Sgueglia JB, Badger CA, Juston AC, Ballantyne J. Forensic applications of a rapid, sensitive and precise multiplex analysis of the four short tandem repeat loci HUMVWF31/A, HUMTHO1, HUMF13A1 and HUMFES/FPS. Electrophoresis. 1995;16:1568–1579
  11. Urquhart A, Kimpton CP, Downes TJ, Gill P. Variation in short tandem repeat sequences — a survey of twelve microsatellite loci for use as forensic identification markers. Int. J. Legal Med. 1994;107:13–20
  12. Evett IW, Gill PD, Lambert JA, Oldroyd N, Frazier R, Watson S, et al. Statistical analysis of data for three British ethnic groups from a new STR multiplex. Int. J. Legal Med. 1997;110:5–9
  13. L.A. Foreman, I.A. Evett, Statistical analyses to support forensic interpretation for a new ten-locus STR profiling system, Int. J. Legal Med. 2000, in press.
  14. Watson S, Kelsey Z, Webb R, Evans J, Gill P. The development of a third generation STR multiplex system (TGM). Progress Forensic Genet. 1998;7:192–194
  15. Editorial, DNA recommendations — further report of the DNA commission of the international society of forensic haemogenetics regarding the use of short tandem repeat systems, Forensic Sci. Int. 87 (1997) 179–184.
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  18. Gill P, Sullivan KM, Werrett DJ. The analysis of hypervariable DNA profiles: problems associated with the objective determination of the probability of a match. Hum. Genet. 1990;85:75–79
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  21. Griffiths RAL, Barber MD, Johnson PE, Gillbard SM, Haywood MD, Smith CD, et al. New reference allelic ladders to improve allelic designation in a multiplex STR system. Int. J. Legal Med. 1998;111:267–272
  22. J.K. Elder, E.M. Southern, Computer-aided analysis of one-dimensional restriction length fragment gels, in: M.J. Bishop, C.K. Rawlings (Eds.), Nucleic Acid and Protein Sequence Analysis, IRL Press, Oxford, 1987, pp. 165–172.
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  25. S.M. Hill, C.N. Maguire, S. Watson, The use of STR multiplex systems for paternity analysis. Forensic Sci. Int. 1999, in press.

PII: S0379-0738(00)00331-5

Forensic Science International
Volume 115, Issue 3 , Pages 207-217 , 15 January 2001

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